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Primary immunodeficiency

Learn how Neria™ infusion sets are used in primary immunodeficiency treatment.
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What is Primary Immunodeficiency?

The human immune system protects the body against infections. When this system fails we call the condition an immunodeficiency1.

People with primary immunodeficiency have an immune system that does not work correctly. This means that people with primary immunodeficiency are more likely to get and become very sick from infections2.

Symptoms

People with primary immunodeficiency are more likely to have symptoms such as2

  • More frequent or repeated infections
  • Infections that last longer than in most people
  • Infections that are hard to treat and do not respond to antibiotics or require IV antibiotics
  • Infections that are more severe and require hospitalization, such as sepsis or abscesses (pus-filled infections) of internal organs 
  • Infections that most people don’t get (sometimes called opportunistic infections)
  • Lack of weight gain or growth in an infant (failure to thrive)
  • Digestive problems, such as chronic diarrhea

Please always consult healthcare professionals about these symptoms and for further advice on primary immunodeficiency. 

Causes

The cause is frequently found to be genetic. Some immunodeficiencies are caused by a single faulty gene and others by a combination of genes. The fault may be inherited, be a new mutation in one of your genes or it may have been inherited from one or both of your parents. Most commonly, a faulty gene does not matter, unless the same fault is inherited from both parents. 1

Treatment for primary immunodeficiency

Immunoglobulin replacement therapy is one of the medical therapies available to treat immunodeficiency. 

Immunoglobulin replacement therapy can be given through an IV, or under the skin, (subcutaneous, SCIg). Both methods are effective at replacing immunoglobulin (IgG) to levels necessary to fight infection3. Always consult healthcare professionals for advice on immunodeficiency.

Our Neria™ infusion sets

When subcutaneous infusion (SCIg) is used, Neria™ infusion sets products can be an option as part of the delivery.

The Neria™ infusion set range is intended for the subcutaneous infusion of immunoglobulins for the treatment of primary immunodeficiency.

The choice of medication and method of administration rely on the assessment of healthcare professionals.

Help with using our products

The Neria™ infusion set range is built with ease of use in mind, but it's crucial to follow the advice of healthcare professionals and consult the Instructions For Use (IFU) when using an infusion set.

Infusion Sets

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Neria™

The Neria™ infusion set is a steel needle infusion set designed for ease of use. The Neria™ infusion set is inserted at a 90-degree angle.

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Infusion Sets

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Neria™Guard

A soft cannula infusion set with an integrated insertion device for simple insertions by the touch of a button. A retractable needle may help prevent accidental needle sticks and increase comfort during insertion.

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Infusion Sets

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Neria™Soft

A soft cannula infusion set for variable angled insertion and can be disconnected at site.

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Infusion Sets

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Neria™Multi

A series of branched steel needle infusion sets designed for subcutaneous infusion of immunoglobulins (IgG) for the treatment of primary immunodeficiency.

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Our Infusion Therapy Areas

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Parkinson's disease

Get an overview of how Neria™ products are used for treatment of Parkinson's disease.

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Thalassemia

Treatments of Thalassemia using Neria™ infusion sets.

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Pain management

Learn about Neria™ infusion sets in the area of pain management and palliative care.

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1.Baxendale Dr. and Henderson K.(2015), "Understanding primary immunodeficiency", Papworth Hospital NHS Foundation Trust.PI_76_Understanding_Primary_Immunodeficiency_review_2015.pdf (royalpapworth.nhs.uk)

2.Center for Disease Control and Prevention: cdc.gov. Reviewed May 20, 2022. Accessed February 26, 2024.https://www.cdc.gov/genomics/disease/primary_immunodeficiency.htm#:~:text=People%20with%20primary%20immunodeficiency%20(PI,how%20early%20they%20are%20detected.

3.American Academy of Allergy Asthma & Immunology: aaaai.org. Accessed February 26, 2024. Immunoglobulin (IgG) Replacement Therapy Defined | AAAA

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