AQUACEL® Ag+ Extra™
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Biofilm is present in at least 78% of hard-to-heal wounds, and it can be invisible to human eyes.8
To avoid any unpleasant obstacles in advanced wound treatment, count on the superiority of AQUACEL® Ag+ Extra™, the only dressing with MORE THAN SILVER™, a three-component technology developed for this fight.
How it Works
Surfactants help to dissolve and remove contamination from surfaces by lowering the surface tension and can be found in products such as skin wipes. MORE THAN SILVER™ technology incorporates BEC (Benzethonium chloride).
BEC reduces the surface tension within a biofilm to enhance the ability of EDTA to remove metal ions in biofilm. BEC and EDTA synergistically work together to disrupt biofilm structures aiding the absorption and removal of the EPS and microorganisms by the dressing.1-5
Chelating agents are compounds that strongly attract and bind certain metal ions, boosting the action of surfactants. MORE THAN SILVER™ technology incorporates EDTA (ethylenediaminetetraacetic acid disodium salt).
EDTA helps disrupt biofilm by removing metal ions that hold the EPS matrix together to expose microorganisms to the antimicrobial effects of the ionic silver.1-4
The AQUACEL® Ag+ Extra™ difference
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Distrupt and destroy Biofilm with AQUACEL ™ Ag+ Extra™
Advancing healing in stalled, deteriorating chronic wounds.
Objective
To demonstrate the ability of AQUACEL® Ag+ dressings to promote healing in chronic wounds that were stalled or deteriorating at baseline.
Results indicated that:
- 78% improved
- 13% healed (average evaluation period of 3.9 weeks)
- 83% progressed in key healing parameters
Selecting the right dressing for your patients will now be easier!
AQUACEL® Ag, AQUACEL® Ag Extra™ and AQUACEL® Ag Ribbon will no longer be available on Drug Tariff from 31.12.2022 making it easier to upgrade to AQUACEL® Ag+ dressings
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ALL the benefits of AQUACEL® Ag and AQUACEL® Ag Extra™
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Addition of MORE THAN SILVER™ Technology, specifically developed to win the battle against biofilm
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Even better outcomes for your patients affected by hard-to-heal wounds, at no extra cost
Learn how AQUACEL® Ag+ Extra™ can help you disrupt and destroy biofilm. Please complete your details below. Once registered, you will have access to the following resources:
- Why is wound biofilm so resistant? How can a dressing destroy it?
- NP Wound Cleansing - Are you doing enough to keep biofilm at bay final?
- Biofilm DFU
References
1. Said J, Walker M, Parsons D, Stapleton P, Beezer AE, Gaisford S. An in vitro test of the efficacy of an anti-biofilm wound dressing. Int J Pharmaceutics. 2014; 474: 177–181. DOI: 10.1016/jijpharm.2014.08.034.
2. Composition comprising antimicrobial metal ions and a quaternary cationic surfactant WO12136968 Parsons World patent application 11th October 2012 .
3. Banin E., Brady K.M. & Greenberg E.P. (2006). Chelator Induced Dispersal and Killing of Pseudomonas aeruginosa Cells in Biofilm. Appl. Environ. Microbiol. 72. 2064 2069.
4. Chen X, Stewart PS, 2000. Biofilm removal caused by chemical treatments. Wat. Res.,34: 4229 4233.
5. Seth AK, Zhong A, Nguyen KT, Hong SJ, Leung KP, Galiano RD, Mustoe TA. Impact of a novel, antimicrobial dressing on in vivo, Pseudomonas aeruginosa wound biofilm: quantitative comparative analysis using a rabbit ear model. Wound Repair Regen. 2014; 22: 712–719. DOI: 10.1111/wrr.12232.
6. Hobot JA, Walker M, Newman GN, Bowler PG, 2008. Effect of Hydrofiber® wound dressings on bacterial ultrastructure. J Electr Micro; 57: 67-75.
7. T. J. Beveridge, W. S. Fyfe. Metal fixation by bacterial cell walls. Canadian Journal of Earth Sciences, 1985, 22(12): 1893-1898, https://doi.org/10.1139/e85-204.
8. Malone M et al. 2017. The prevalence of biofilm in chronic wounds: a systematic review and meta-analysis of published data. JWC; 20-25.
9. Metcalf DG, Parsons D, Bowler PG. Clinical safety and effectiveness evaluation of a new antimicrobial wound dressing designed to manage exudate, infection and biofilm. Int Wound J 2017; 14: 203-213