Parkinson's disease
What is Parkinson’s disease?
Symptoms
People living with Parkinson's disease are likely to experience notable symptoms. All symptoms are best identified and addressed in collaboration with a healthcare professional. As a general reference, some main symptoms are:1
- Muscle tremors
- Slower and/or rigid body movement
- Unsteady posture
- Small handwriting
Causes
Parkinson's disease may be described as a loss of nerve cells in the brain. Without these nerve cells, dopamine levels in the brain drop. As dopamine is essential to the body's ability to regulate movement, the loss of it can lead to the symptoms listed above.
Since research is still ongoing to understand more about Parkinson's disease, there is still a lot to learn. What is known is that Parkinson's disease can be passed down through genetics, but no external causes/triggers have been confirmed.
Treatment of Parkinson’s disease with apomorphine
Apomorphine is used to treat Parkinson's disease. It may be prescribed to patients who aren't responding well to other treatments or who experience frequent "off" periods and less control.
Apomorphine is administered subcutaneously:
- By intermittent injections with a ready-loaded disposable pen
- As a continuous infusion using a syringe driver infusion pump with a pre-filled syringe
Continous Infusion therapy
Continuous infusion therapy with apomorphine can help improve the quality of life for some patients. The patient uses a battery-driven, syringe-driver infusion pump to deliver a specified continuous amount of the drug when required, adjusting the amount as needed during the day.2 To deliver apomorphine, the patient inserts an infusion set under the skin and connects it to the infusion pump.
Our Neria™ infusion sets
Neria™Guard, Neria™Soft & Neria™ infusion sets are intended for the subcutaneous infusion of apomorphine for Parkinson’s disease.
Neria™Guard is also intended for the subcutaneous infusion of foslevodopa/foscarbidopa for Parkinson’s disease.
The choice of medication and method of administration rely on the assessment of healthcare professionals.
Infusion Sets
Neria™
The Neria™ infusion set is a steel needle infusion set designed for ease of use. The Neria™ infusion set is inserted at a 90-degree angle.
View detailsInfusion Sets
Neria™Guard
A soft cannula infusion set with an integrated insertion device for simple insertions by the touch of a button. A retractable needle may help prevent accidental needle sticks and increase comfort during insertion.
View detailsInfusion Sets
Neria™Soft
A soft cannula infusion set for variable angled insertion and can be disconnected at site.
View detailsHelp with using our products
Below you can find some basic info about using a Neria™Guard infusion set.
How to use the Neria™Guard infusion sets
Watch our instruction videos and quickly learn how to use the Neria™Guard infusion set.
Please refer to the Instructions For Use (IFU) for a complete list of all information.
The Neria™ product range
Neria™Guard, Neria™Soft & Neria™infusion sets are tested and used for subcutaneous infusion treatment for Parkinson’s disease.
The Neria™ product range offers a wide variety of infusion sets with different features to help provide more options for patients with Parkinson's disease.
For an overview of our Neria™ infusion set range for Parkinson's disease, including specifications, please see the table below*.
|
Product Specifications |
Neria™Guard |
Neria™ |
Neria™Soft |
||
|
Cannula |
Soft |
Stainless Steel |
Soft |
||
|
Insertion angle |
90 degrees |
90 degrees |
20-45 degrees |
||
|
Disconnection feature |
Yes at site |
No |
Yes at site |
||
|
Needle / Introducer needle gauge |
G27 |
G27 or G29 |
G27 |
||
|
Needle lengths |
6 or 9 mm |
6, 8, 10 |
13 or 17mm |
||
|
Tubing lengths |
12, 60, 110 cm |
60, 110 cm |
60, 110 cm |
||
|
Adhesive |
Built-in |
Built-in |
Built-in |
||
|
Hidden needle |
Yes |
- |
- |
||
|
Intended to use for Parkinson’s disease |
Yes |
Yes |
Yes |
*For information about type of medication that has been tested for use with the infusion set, please refer to the Instructions For Use.
Our Infusion Therapy Areas
Therapy area
Pain management
Learn about Neria™ infusion sets in the area of pain management and palliative care.
Read moreTherapy area
Thalassemia
Treatments of Thalassemia using Neria™ infusion sets.
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Primary immunodeficiency
Learn how Neria™ infusion sets are used in primary immunodeficiency treatments.
Read more1. Cleveland Clinic: my.clevelandclininc.org. Reviewed April 15, 2022. Accessed February 1, 2024. https://my.clevelandclinic.org/health/diseases/8525-parkinsons-disease-an-overview
2. Katzenschlager R, Poewe W, Rascol O, Trenkwalder C, Deuschl G, Chaudhuri KR, Henriksen T, van Laar T, Spivey K, Vel S, Staines H, Lees A. Apomorphine subcutaneous infusion in patients with Parkinson's disease with persistent motor fluctuations (TOLEDO): a multicentre, double-blind, randomised, placebo-controlled trial. Lancet Neurol. 2018 Sep;17(9):749-759. doi: 10.1016/S1474-4422(18)30239-4. Epub 2018 Jul 25. PMID: 30055903.
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