Aquacel® Ag dressings have been replaced by Aquacel® Ag+ dressings
Remember + when you prescribe
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We have simplified our anti-infective range and discontinued the old Aquacel® Ag, Aquacel® Ag Extra and Aquacel® Ag Ribbon dressings. This means they are no longer on Drug Tariff or available on prescription.
These have been replaced with Aquacel® Ag+ Dressings, our award winning anti-infective dressing:
ALL the benefits of old Aquacel® Ag
The addition of MORE THAN SILVER™ Technology, specifically developed to win the battle against biofilm
Even better outcomes for your patients at no extra cost
Remember to update your codes, and include the + or write the new PIP codes when prescribing or your patients may experience delays.
Any prescriptions for Aquacel® Ag dressings should be returned to the surgery for amending and not be dispensed.
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How it Works
Surfactants help to dissolve and remove contamination from surfaces by lowering the surface tension and can be found in products such as skin wipes. MORE THAN SILVER™ technology incorporates BEC (Benzethonium chloride).
BEC reduces the surface tension within a biofilm to enhance the ability of EDTA to remove metal ions in biofilm. BEC and EDTA synergistically work together to disrupt biofilm structures aiding the absorption and removal of the EPS and microorganisms by the dressing1-5.
Chelating agents are compounds that strongly attract and bind certain metal ions, boosting the action of surfactants. MORE THAN SILVER™ technology incorporates EDTA (ethylenediaminetetraacetic acid disodium salt).
EDTA helps disrupt biofilm by removing metal ions that hold the EPS matrix together to expose microorganisms to the antimicrobial effects of the ionic silver1-4.
The AQUACEL® Ag+ Extra™ difference
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Distrupt and destroy Biofilm with AQUACEL ™ Ag+ Extra™
Advancing healing in stalled, deteriorating chronic wounds.
Objective
To demonstrate the ability of AQUACEL® Ag+ dressings to promote healing in chronic wounds that were stalled or deteriorating at baseline.
Results indicated that:
- 78% improved
- 13% healed (average evaluation period of 3.9 weeks.
- 83% progressed in key healing parameters
For more information about the discontinuation, support in updating your codes or to Learn more about how Aquacel® Ag+ Extra can help you disrupt and destroy biofilm, please complete your details below.
References
1. Said J, Walker M, Parsons D, Stapleton P, Beezer AE, Gaisford S. An in vitro test of the efficacy of an anti-biofilm wound dressing. Int J Pharmaceutics. 2014; 474: 177–181. DOI: 10.1016/jijpharm.2014.08.034.
2. Composition comprising antimicrobial metal ions and a quaternary cationic surfactant WO12136968 Parsons World patent application 11th October 2012 .
3. Banin E., Brady K.M. & Greenberg E.P. (2006). Chelator Induced Dispersal and Killing of Pseudomonas aeruginosa Cells in Biofilm. Appl. Environ. Microbiol. 72. 2064 2069.
4. Chen X, Stewart PS, 2000. Biofilm removal caused by chemical treatments. Wat. Res.,34: 4229 4233.
5. Seth AK, Zhong A, Nguyen KT, Hong SJ, Leung KP, Galiano RD, Mustoe TA. Impact of a novel, antimicrobial dressing on in vivo, Pseudomonas aeruginosa wound biofilm: quantitative comparative analysis using a rabbit ear model. Wound Repair Regen. 2014; 22: 712–719. DOI: 10.1111/wrr.12232.
6. Hobot JA, Walker M, Newman GN, Bowler PG, 2008. Effect of Hydrofiber® wound dressings on bacterial ultrastructure. J Electr Micro; 57: 67-75.
7. T. J. Beveridge, W. S. Fyfe. Metal fixation by bacterial cell walls. Canadian Journal of Earth Sciences, 1985, 22(12): 1893-1898, https://doi.org/10.1139/e85-204.
8. Malone M et al. 2017. The prevalence of biofilm in chronic wounds: a systematic review and meta-analysis of published data. JWC; 20-25.
9. Metcalf DG, Parsons D, Bowler PG. Clinical safety and effectiveness evaluation of a new antimicrobial wound dressing designed to manage exudate, infection and biofilm. Int Wound J 2017; 14: 203-213