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AQUACEL® Ag+ Extra™

Disrupt and destroy biofilm
a green and white box ;

Biofilm is present in at least 78% of hard-to-heal wounds, and it can be invisible to human eyes.8

To avoid any unpleasant obstacles in advanced wound treatment, count on the superiority of AQUACEL® Ag+ Extra™, the only dressing with MORE THAN SILVER™, a three-component technology developed for this fight.

SIGN UP FOR HELPFUL RESOURCES

How it Works

Surfactants help to dissolve and remove contamination from surfaces by lowering the surface tension and can be found in products such as skin wipes. MORE THAN SILVER™ technology incorporates BEC (Benzethonium chloride).

BEC reduces the surface tension within a biofilm to enhance the ability of EDTA to remove metal ions in biofilm. BEC and EDTA synergistically work together to disrupt biofilm structures aiding the absorption and removal of the EPS and microorganisms by the dressing.1-5

Chelating agents are compounds that strongly attract and bind certain metal ions, boosting the action of surfactants. MORE THAN SILVER™ technology incorporates EDTA (ethylenediaminetetraacetic acid disodium salt).

EDTA helps disrupt biofilm by removing metal ions that hold the EPS matrix together to expose microorganisms to the antimicrobial effects of the ionic silver.1-4

A broad-spectrum antimicrobial.
 
Silver is a safe, broad-spectrum antimicrobial that is only effective in its ionic form. Attracted to sites on bacterial cell walls, it accumulates and then enters the cell, where it damages the DNA, denatures proteins and enzymes, and interferes with protein synthesis.
 
The cell wall becomes porous and the contents leak out, leading to cell death.6, 7

The AQUACEL® Ag+ Extra™ difference

Distrupt and destroy Biofilm with AQUACEL ™ Ag+ Extra™ ;

Distrupt and destroy Biofilm with AQUACEL ™ Ag+ Extra™

Advancing healing in stalled, deteriorating chronic wounds.

Multicentre clinical study monitoring the use of AQUACEL® Ag+ dressings on 111 patients with non-healing wounds.9
timeline ;

Objective

To demonstrate the ability of AQUACEL® Ag+ dressings to promote healing in chronic wounds that were stalled or deteriorating at baseline.

Results indicated that:

  • 78% improved
  • 13% healed (average evaluation period of 3.9 weeks)
  • 83% progressed in key healing parameters

 

Selecting the right dressing for your patients will now be easier!

AQUACEL® Ag, AQUACEL® Ag Extra™ and AQUACEL® Ag Ribbon will no longer be available on Drug Tariff from 31.12.2022 making it easier to upgrade to AQUACEL® Ag+ dressings

  • ALL the benefits of AQUACEL® Ag and AQUACEL® Ag Extra™
  • Addition of MORE THAN SILVER™ Technology, specifically developed to win the battle against biofilm
  • Even better outcomes for your patients affected by hard-to-heal wounds, at no extra cost

Learn how AQUACEL® Ag+ Extra™ can help you disrupt and destroy biofilm. Please complete your details below. Once registered, you will have access to the following resources:

  • Why is wound biofilm so resistant? How can a dressing destroy it?
  • NP Wound Cleansing - Are you doing enough to keep biofilm at bay final?
  • Biofilm DFU
Select a product type
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How we use information: Treating your personal data with care is important to us. Please read our privacy policy where you can find detailed information on how we protect and use personal data. 

How we use information: Treating your personal data with care is important to us. Please read our privacy policy where you can find detailed information on how we protect and use personal data. 

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You can opt out of receiving marketing messages anytime by contacting us by telephone at 1800 339 412, or by email at Connection.au@convatec.com. You may also click on the ‘Unsubscribe’ link in the footer of the emails you will receive.

References

1. Said J, Walker M, Parsons D, Stapleton P, Beezer AE, Gaisford S. An in vitro test of the efficacy of an anti-biofilm wound dressing. Int J Pharmaceutics. 2014; 474: 177–181. DOI: 10.1016/jijpharm.2014.08.034.

2. Composition comprising antimicrobial metal ions and a quaternary cationic surfactant WO12136968 Parsons World patent application 11th October 2012 .

3. Banin E., Brady K.M. & Greenberg E.P. (2006). Chelator Induced Dispersal and Killing of Pseudomonas aeruginosa Cells in Biofilm. Appl. Environ. Microbiol. 72. 2064 2069.

4. Chen X, Stewart PS, 2000. Biofilm removal caused by chemical treatments. Wat. Res.,34: 4229 4233.

5. Seth AK, Zhong A, Nguyen KT, Hong SJ, Leung KP, Galiano RD, Mustoe TA. Impact of a novel, antimicrobial dressing on in vivo, Pseudomonas aeruginosa wound biofilm: quantitative comparative analysis using a rabbit ear model. Wound Repair Regen. 2014; 22: 712–719. DOI: 10.1111/wrr.12232.

6. Hobot JA, Walker M, Newman GN, Bowler PG, 2008. Effect of Hydrofiber® wound dressings on bacterial ultrastructure. J Electr Micro; 57: 67-75.

7. T. J. Beveridge, W. S. Fyfe. Metal fixation by bacterial cell walls. Canadian Journal of Earth Sciences, 1985, 22(12): 1893-1898, https://doi.org/10.1139/e85-204.

8. Malone M et al. 2017. The prevalence of biofilm in chronic wounds: a systematic review and meta-analysis of published data. JWC; 20-25.

9. Metcalf DG, Parsons D, Bowler PG. Clinical safety and effectiveness evaluation of a new antimicrobial wound dressing designed to manage exudate, infection and biofilm. Int Wound J 2017; 14: 203-213

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