Clinical study results
Kogan, et al. 2004 [+]
Vloeman, et al. 2001 [+]
In a non-comparative study of 84 patients with partial-thickness burns receiving AQUACEL® Hydrofiber® Wound Dressing
:2
- In 50% of patients, the wounds healed completely within 10 days (range = 1-17)
- On average 82.9% of the original burn area healed without surgical intervention
- 67 patients required only 1 dressing application (1.6 dressing changes were undertaken on the remaining patients)
Piaggesi, et al. 2001 [+]
In a randomized trial of 20 patients with diabetic foot ulcers comparing AQUACEL® Hydrofiber® Wound Dressing
with saline-moistened gauze for the management of deep diabetic foot ulcers:3
- Rate of granulation and reduction in lesional volume were significantly better in deep diabetic foot ulcers managed with AQUACEL® Hydrofiber® Wound Dressing
than in those managed with saline-moistened gauze (P<0.01)
Harding, et al. 2001 [+]
Ravenscroft, et al. 2001 [+]
In a randomized controlled trial of 183 patients, comparing AQUACEL® Hydrofiber® Wound Dressing
(covered with Tegaderm™, a) with Cutiplast™, b, after hip and knee surgery:5
- Wounds managed with the AQUACEL®/Tegaderm™ dressing combination were 5.8 times more likely to heal without complications than Cutiplast™ treated wounds (P<0.00001)
- Only 2.4% of the wounds managed with AQUACEL®/Tegaderm™ dressing combination had wounds with blisters versus 22.5% in the Cutiplast™ group.
- "...dressing pain score is statistically lower for the patients receiving the AQUACEL®/Tegaderm™ dressing combination (P<0.001) [than Cutiplast™]"
- AQUACEL® Hydrofiber® Wound Dressing
(covered with Tegaderm™) requires on average 3.6 dressing changes, whereas Cutiplast™ requires 4.1 dressing changes (P=0.03)
Foster, et al. 2000 [+]
Foster, et al. 1997 [+]
In a randomized trial of 40 patients, comparing AQUACEL® Hydrofiber® Wound Dressing
with ribbon gauze and proflavine dressing in surgical wounds left to heal by secondary intention:7
- Patients in the AQUACEL® Hydrofiber® Wound Dressing
group experienced significantly less pain on removal of the first dressing versus the ribbon gauze group (P=0.006)
- 60% of wounds managed with AQUACEL® Hydrofiber® Wound Dressing
responded that the 1st dressing change could have taken place at home versus 15% for ribbon gauze (P=0.02)
- Pain was a key factor in the ribbon gauze group for patients wishing to have dressings changed in hospital
References [+]
- Kogan L, Moldavsky M, Szvalb S, Govrin-Yehudain J. Comparative study of Aquacel and Silverol treatment in burns. Ann Burns Fire Disasters 2004; 17(4):201–207.
- Vloemans AF, Soesman AM, Kreis RW, Middelkoop E. A newly developed hydrofibre dressing, in the treatment of partial-thickness burns. Burns. 2001;27[2]:167-173.
- Piaggesi A, Baccetti F, Rizzo L, Romanelli M, Navalesi R, Benzi L. Sodium carboxylmethyl-cellulose dressings in the management of deep ulcerations of diabetic foot. Diabet Med. 2001;18(4):320-324.
- Harding KG, Price P, Robinson B, Thomas S, Hofman D, 2001. Cost and dressing evaluation of Hydrofiber and alginate dressings in the management of community-based patients with chronic leg ulceration. Wounds 13(6): 229-236.
- Ravenscroft MJ, Harker J, Buch KA. A prospective, randomised, controlled trial comparing wound dressings used in hip and knee surgery: Aquacel and Tegaderm versus Cutiplast. Ann R Coll Surg Engl 2006; 88(1):18-22.
- Foster L, Moore P, Clark S. A comparison of hydrofibre and alginate dressings on open acute surgical wounds. J Wound Care 2000; 9(9): 442-5.
- Foster L, Moore P. The application of a cellulose-based fibre dressing in surgical wounds. J of Wound Care. 1997:6 (10):469-473
Notes [+]
- Tegaderm is a trademark of 3M.
- Cutiplast is a trademark of Smith and Nephew.
- Sorbsan is a trademark of UDL Laboratories, Inc